Lifeboat Foundation

Circa 2019 o.o

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The extracellular matrix (ECM) including three-dimensional (3D) network and bioelectricity can profoundly influence cell development, migration, and functional expression. In a new report now published on Science Advances, Tong Li and a research team in chemistry, nanotechnology, bioelectronics and advanced materials in China, developed an electromechanical coupling bio-nanogenerator abbreviated bio-NG inspired by biophysical cues of the extracellular matrix. The device contained highly discrete piezoelectric fibers to generate piezo potential of up to millivolts to provide in situ electrical stimulation for living cells.

Circa 2019 o.o

The dream of resurrecting species like the woolly mammoth via genetic engineering is old enough that I remember reading articles about it in school 30 years ago. We may never be able to recover enough pristine genetic material from an intact woolly mammoth to make that approach feasible, but scientists working on the remains of the frozen mammoth known as Yuka have taken an incredible step nonetheless, demonstrating that at least some cell functions can remain intact after nearly 30,000 years.

Yuka, found in 2,010 is a juvenile woolly mammoth, considered to be the most intact and well-preserved mammoth ever found. That was critical to the researchers’ efforts — earlier tests in 2009 with a less-well-preserved but younger specimen at 15,000 years old yielded no positive results at all.

Continue reading “Scientists Revive 28,000-Year-Old Woolly Mammoth Cells in Mice” »

The Loihi 2 chip doesn’t just significantly boost the number of neurons from its first iteration, it also greatly expands their functionality.

Interestingly, the nuclear protein histone H4 was detected, which is reminiscent of the retention of nuclear components in the remains (Fig. 2c). Search against the database of all mammalian species identified other nuclear proteins, such as histones, histone chaperones, proteins implicated in mRNA processing or transport and nuclear membrane proteins (Supplementary Table S2). In addition, we identified two well-characterised epigenetic modifications on histone molecules, methylation of H3K79 and H4K20 (Supplementary Fig. S2A and B), which are involved in transcriptional regulation and genome maintenance^18,19. Our high-sensitive proteomic analysis suggests that the remains retain nuclear components.

These findings motivated us to seek cell nuclei from the muscle remains. Although DAPI-positive and autofluorescence-negative nucleus-like structures were rarely found (Supplementary Figs S3 and S4), we chose the autofluorescence-negative structures for the subsequent live-cell imaging of nuclear-transferred embryos since autofluorescence disturbs accurate tracing of fluorescent-tagged proteins. In total, 88 nucleus-like structures were collected from 273.5 mg mammoth tissue in 5 independent experiments (Supplementary Table S7). Our immunostaining protocol developed for single suspended cells from remains (Supplementary Fig. S5) revealed that these structures were positive for lamin B2 and histone H3, both of which were identified by mass spectrometry (Fig. 3a and Supplementary Fig. S6), suggesting that cell nuclei are, at least partially, sustained even in over a 28,000 year period.

Whether these different organisations want to land astronauts, install a human outpost or mine minerals and make rocket fuel on the moon, it still lacks an exceptional and important asset– A lunar radio Telescope. Why? Because this development will be uniquely poised to answer one of humanity’s greatest questions: What is our cosmic origin?
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All the lunar missions that are being planned along with all other missions that different organizations want to accomplish, will be of no use if we don’t seek answers to fundamental questions like “what is the universe made up of? What are we made up of?” And a telescope on the far side of the moon will help us answer these important questions!! So let’s take a look at why this is important and what NASA is planning to do about it.
As mentioned earlier the universe constantly beams its history to us. For instance, the information of what happened long ago in the universe is contained in the long length radio waves that are present everywhere throughout the universe and most likely hold the details about how the first black holes and stars were formed. But there’s a problem. Our noisy radio signals and our atmosphere block these signals from coming to the earth and we can’t read them. The far side of the moon is the best place in the inner solar system to monitor these low-frequency radio waves and help us in detecting certain faint ‘fingerprints’ that the big bang left on the cosmos. The problem with our earth bound telescopes is that they encounter too much interference for electromagnetic pollution caused by human activity, whether it is short-wave broadcasting or maritime communication. On the top of that our ionosphere blocks the longest wavelengths from reaching our earth-based telescopes in the first place. We need these signals to understand and learn whether our universe inflated rapidly in the first trillionth of a trillionth of second after the big bang.

This is the reason why NASA is in the early stages of planning what it would take to build an automated research telescope on the dark side of the moon. One of the most ambitious proposals is to build the Lunar Crater radio telescope or the LCRT
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Continue reading “NASA Plan To Put A Telescope On The Dark Side Of The Moon” »

India is entering the space industry.

India is opening doors for private companies to enter space.
PM Narendra Modi launched the Indian Space Association that will serve as a “single-window” for matters of space technology.
What is India’s game plan to win the global space race?
Palki Sharma tells you.

Continue reading “Gravitas: India’s game plan to win the global space race” »

SpaceX’s first all-civilian mission to orbit was a success. Here’s what comes next.

Last week, SpaceflightNow reported that NASA’s upcoming crewed mission to the International Space Station would use a new Crew Dragon capsule. The mission, set for October 30 will feature a capsule named Endurance by the four-person crew. The news means that the crew won’t have to wait for SpaceX to refurbish one of its other two capsules.

That means the crew will take off less than two months after the Inspiration4 mission, the first all-civilian mission to orbit. On September 30 NASA announced that Crew-3 would launch no earlier than 2:43 a.m. Eastern time on Saturday, October 30. It will be SpaceX’s fourth crewed mission for NASA and its fifth crewed mission overall.

Continue reading “SpaceX Crew-3 capsule name, launch date, and astronauts for next mission” »

Astronomers have confirmed the existence of a gigantic comet — and they say it’s headed towards Earth.

The comet was discovered by University of Pennsylvania astronomers Pedro Bernadinelli and Gary Bernstein, according to The Daily Beast. The pair initially found evidence of a 60 to 100 mile wide comet seven years ago and have finally released a paper confirming it late last month in the journal The Astrophysical Journal Letters.

Dubbed the Bernardinelli-Bernstein (BB) comet, the astronomers also described it as the “nearly spherical cow of comets” in the paper.